Molecular evidence suggests that each retina expresses a different visualpigment.
2
A new high-resolution structure is reported for bovine rhodopsin, the visualpigment in rod photoreceptor cells.
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Goldfish has a UV-sensitive visualpigment (S group) localized in miniature single cone cells.
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Activation of the visualpigment by light in rod and cone photoreceptors initiates our visual perception.
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The visual cycle is a chain of biochemical reactions that regenerate visualpigment following exposure to light.
1
Vision relies on photoactivation of visualpigments in rod and cone photoreceptor cells of the retina.
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For example, rod and cone visualpigments couple to distinct variants of the heterotrimeric G protein transducin.
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Vertebrate rod and cone photoreceptors require continuous supply of chromophore for regenerating their visualpigments after photoactivation.
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There are exceptions, the firefly squid Watasenia scintillans possesses three kinds of visualpigments in the eye.
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Although nocturnal and diurnal geckos have rod- and cone-based retinas, respectively, they have phylogenetically closely related visualpigments.
1
Type E lesions can be described as drusen-like retinalpigment detachments.
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FAG showed window defects due to atrophy of retinalpigment epithelium.
3
In persons susceptible to AMD, the retinalpigment epithelium becomes dysfunctional.
4
These genes are expressed preferentially in the retina or the retinalpigment epithelium.
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Optical coherence tomography disclosed that the strands existed at the retinalpigment epithelium level.
1
Our studies add another dimension to an essential role for LPCAT1 in retinalphotoreceptor homeostasis.
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Conclusions: Transplantation of fetal retinalphotoreceptor suspensions into the subretinal space was achieved safely in nine subjects.
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These data suggest that Otx2 plays a functional role in the maturation of retinalphotoreceptor and bipolar cells.
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Here we present evidence suggesting that Qo2 must be controlled differently in the retinalphotoreceptor cells of the honeybee drone.
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Emerging evidence also indicates that NAS and its derivatives have neuroprotective properties and protect retinalphotoreceptor cells from light-induced degeneration.
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Rhodopsins are prototypical GPCRs that detect photons in retinalphotoreceptor cells and trigger a phototransduction cascade that culminates in neuronal signaling.
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Retinitis pigmentosa (RP) is a hereditary disease that leads to the progressive degeneration of retinalphotoreceptor cells and to blindness.
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Phototransduction is carried out by a signaling pathway that links photoactivation of visual pigments in retinalphotoreceptor cells to a change in their membrane potential.
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The present study aimed to investigate the mechanisms that mediate the protective effects of pyridoxamine (PM) on light-damaged retinalphotoreceptor cells in diabetic mice.
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Degeneration or dysfunction of retinalphotoreceptors is frequently observed in diverse ciliopathies.
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Multitissue Northern blot analysis and in situ hybridization studies indicate that SPACR expression is restricted to retinalphotoreceptors.
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The ERG a-wave is the light-induced hyperpolarization of retinalphotoreceptors, and the b-wave is the depolarization of ON-bipolar cells.
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Light absorbed by retinalphotoreceptors triggers a cascade of reactions that initiate cGMP hydrolysis, cation channel closure and membrane hyperpolarization.
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Here, we study a canonical pair of sister cell types, retinalphotoreceptors and bipolar cells, to identify the key cis-regulatory features that distinguish them.
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Rat AA-NAT mRNA was detected exclusively in the retinalphotoreceptors in the outer nuclear layer-lowduring the day and increased more than threefold at night.